Adults and pediatrics: Acute diarrhea: The initial dose is 2 capsules (4 mg) for adults and 1 capsule (2 mg) for children; followed by 1 capsule (2 mg) after every subsequent loose stool.
Chronic diarrhea: The initial dose is 2 capsules (4 mg) daily for adults and 1 capsule (2 mg) daily for children; this initial dose should be adjusted until 1-2 solid stools a day are obtained, which is usually achieved with a maintenance dose of 1-6 capsules (2 mg-12 mg) daily.
The maximum dose for acute and chronic diarrhea is 8 capsules (16 mg) daily for adults; in children it must be related to the body weight (3 capsules/20 kg) but should not exceed a maximum of 8 capsules per day.
Pediatrics (under 2 years of age):
Loperamide HCl should not be used in children under 2 years of age.
Elderly: No dose adjustment is required for the elderly.
Renal impairment: No dose adjustment is required for patients with renal impairment.
Hepatic impairment: Although no pharmacokinetic data are available in patients with hepatic impairment, Loperamide HCl should be used with caution in such patients because of reduced first-pass metabolism.
Administration: The capsules should be taken with liquid.
What should the patient do if they miss a dose: Continue medication based on dosage and/or consult a doctor.
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