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Ilosone DS: General: Since erythromycin is excreted principally by the liver, caution should be exercised in administering the antibiotic to patients with impaired hepatic function.
When indicated, incision and drainage or other surgical procedures should be performed in conjunction with antibiotic therapy.
Carcinogenesis/Mutagenesis: Two year oral studies conducted in rats with erythromycin did not provide evidence of tumorigenicity or mutagenicity.
Use in Pregnancy & Lactation: See USE IN PREGNANCY & LACTATION section for further information.
Use in children: Several reports of infantile hypertrophic pyloric stenosis have been reported in newborn infants receiving various erythromycin products, including erythromycin estolate. Erythromycin should be used cautiously in the first three months of life. (See Use in Pregnancy & Lactation, Indications/Uses and Dosage and Administration.)
Ilosone 200: Erythromycin should not be given to patients with impaired liver function or to patients who have developed jaundice or other symptoms of liver toxicity during previous treatment with erythromycin.
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