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For the treatment of adult patients with locally advanced or metastatic breast cancer who have progressed after at least one chemotherapeutic regimen for advanced disease (see PHARMACOLOGY: PHARMACODYNAMICS: CLINICAL STUDIES under ACTIONS). Prior therapy should have included an anthracycline and a taxane in either the adjuvant or metastatic setting unless patients were not suitable for these treatments.
For the treatment of soft tissue sarcoma.
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