Genpharm BCG Vaccine Special Precautions

Information of Antituberculosis Drugs: The Minimum Inhibitory Concentration (MIC) towards the Mycobacterium bovis BCG Moscow strain 361-I is indicated in mentioned table as follows. (See table.)

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In case of systemic or persistent local infection with BCG vaccine occurs, expert advice should be taken for the necessary treatment. BCG Moscow strain 361-I is resistant to pyrazinamide.
Use in Children: Special Case of Children Born to HIV Seropositive Mothers: The obligatory passage of maternal antibodies of the IgG type through the placenta makes it impossible to interpret the serology of the child until the age of about 9-10 months (persistence of the maternal antibodies has been detected up to 14 months). It is therefore necessary to wait until the child has been found to be seronegative, as determined by immuno-transfer (Western Blot) with the support, if necessary, of techniques for detecting the viral genome, before confirming that the child is not infected.