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Hepatic: Hepatic function disorder such as elevations of GOT, GPT, ALP may occur.
Renal: Elevations of BUN, creatinine may occur.
Gastrointestinal: Nausea, vomiting, anorexia, stomatitis, diarrhea, abdominal pain, and constipation may occur.
Hypersensitivity: Rash may occur.
Dermatologic: Severe alopecia, erythema, pruritus may occur.
Nervous System: carpopedal numbness, headache may occur.
Respiratory: Occasionally, ECG abnormality, arrhythmia, hypotension may occur.
Others: Malaise, flush may occur. Adverse effects including bone marrow depression may vary by concomitant administration with other antineoplastic agents or radiotherapy.
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