Desowen Special Precautions

Prolonged use of corticosteroids of medium potency on the face is associated with a risk of occurrence of corticosteroid-related dermatitis that is, paradoxically, corticosteroid-responsive, with a rebound after each treatment discontinuation. Gradual withdrawal by tapering, which is particularly difficult, is then required.
The product is not recommended in patients with acne, rosacea and perioral dermatitis.
The product should not be applied on skin areas affected by bacterial and mycobacterial, viral, fungal, parasitic infections or ulcerous wounds.
Due to the systemic penetration of corticosteroids, treatment of large skin areas or application under occlusive dressings may induce the systemic effects of systemic corticosteroid therapy, particularly in infants and young children. Those effects consist in a cushingoid syndrome and growth retardation. The effects resolve following treatment discontinuation, but abrupt discontinuation may be followed by acute adrenal failure.
In the event of application to the eyelid, the duration of treatment must be limited. Prolonged application exposes the patient to the risk of glaucoma.
Visual disturbance: Visual disturbance may be reported with systemic and topical corticosteroid use.
If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use of systemic and topical corticosteroids.
Special precautions for use: In infants, corticosteroids of medium potency should preferably be avoided.
Particular attention must be paid to avoid spontaneous occlusive phenomena, which occur in skin folds or under diapers.
In the event of bacterial or fungal superinfection of a corticosteroid-responsive dermatosis, use specific treatment before the corticosteroid treatment.
If signs of local intolerance develop, discontinue the treatment and conduct an etiologic investigation.
Effects on the ability to drive and use machines: Not applicable.