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Pharmacology: Pharmacodynamics: Dermatological Corticosteroids: Dermatological corticosteroids are divided into 4 potency levels on the basis of cutaneous vasoconstriction tests: very high, high, medium and low potency.
Desonide (Desowen) has medium potency.
Desonide acts on some inflammatory processes (e.g. contact hypersensitivity) and the pruriginous effect related to them.
Vasoconstrictor. Inhibitor of cell proliferation.
Pharmacokinetics: The degree of dermal barrier crossing, and systemic effects depend on the magnitude of the area treated, the degree of epidermal impairment and the duration of treatment. The effects are more likely, the longer the duration of treatment.
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