Cytosplat Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Cisplatin

Indications/Uses

Metastatic testicular & ovarian tumors, advanced bladder carcinoma, testicular/ovarian neoplasms, head & neck cancer, cervical carcinoma, lung cancer.

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Dosage/Direction for Use

Testicular, bladder or prostatic cancer 15-20 mg/m² IV once for 5 consecutive days every 3 wk or 25-35 mg/m² once wkly. Ovarian neoplasm 50-70 mg/m² once every 4 wk or follow dosage for testicular neoplasm. Head & neck cancer 10-20 mg/m² once daily for 5 consecutive days every 3 wk or 50-70 mg/m² once every 4 wk. Lung carcinoma 70-90 mg/m² once every 4 wk or 20 mg/m² once daily for 5 consecutive days every 3 wk. Esophageal cancer 50-70 mg/m² once every 4 wk or 15-20 mg/m² once daily for 5 consecutive days every 3 wk. Uterine & neck cancer 15-20 mg/m² once daily for 5 consecutive days every 3 wk or 70-90 mg/m² once every 4 wk. Gastric cancer 70-90 mg/m² once every 4 wk.

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Overdosage

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Contraindications

Hypersensitivity. Preexisting renal impairment. Pregnancy & lactation.

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Special Precautions

Renal or hepatic impairment, bone marrow depression, hearing disorder. Infection & bleeding tendency. May have an anti-fertility effect. Do not use Al-containing needles or IV sets. Do not inject w/ other anti-tumor agents. Pregnancy & lactation. Women of childbearing potential. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nausea, vomiting, diarrhea, anorexia, constipation, stomatitis, nephrotoxicity; myelosuppression, leucopenia, thrombocytopenia, anemia; ototoxicity, rash; neurotoxicity; loss of taste, seizures, peripheral neuropathies; transient elevations of serum AST (SGOT), ALT (SGPT) & bilirubin conc; CHF, palmus, tachycardia, atrial fibrillation; serious electrolyte disturbances; mild alopecia, hiccups, myalgia, pyrexia, gingival platinum line.

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Drug Interactions

Increased depressed bone marrow function in concomitant use w/ other antitumor agents & radiation exposure. Increased ototoxicity or nephrotoxicity w/ aminoglycoside antibiotics.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Cytosplat detailed prescribing information

Storage

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Description

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Action

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MIMS Class

Cytotoxic Chemotherapy

ATC Classification

L01XA01 - cisplatin ; Belongs to the class of platinum-containing antineoplastic agents. Used in the treatment of cancer.

Regulatory Classification

Presentation/Packing

Form

Cytosplat soln for infusion 10 mg/10 mL

Packing/Price

1's

Form

Cytosplat soln for infusion 50 mg/50 mL

Packing/Price

1's

Cytosplat

cisplatin

Manufacturer:

Korea United Pharma

Distributor:

Qualimed