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Cozalyn 100

Cozalyn 100

losartan

Manufacturer:

Dagon Pharma

Distributor:

Philgen
Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing
Concise Prescribing Info
Contents
Losartan K
Indications/Uses
Management of HTN, heart failure & in MI.
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Dosage/Direction for Use
HTN 50 mg once daily, may be increased if necessary to 100 mg daily in 1 or 2 divided doses. Elderly >75 yr, & patient w/ moderate to severe renal impairment (CrCl <20 mL/min) or intravascular fluid depletion Initially 25 mg once daily. Patient w/ hepatic impairment Consider reduced dose.
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Overdosage
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Administration
May be taken with or without food.
Contraindications
Coadministration w/ aliskiren in patients w/ diabetes.
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Special Precautions
Symptomatic hypotension may occur after initiation of treatment in patients w/ an activated renin-angiotensin system (RAS) eg, vol- or salt-depleted patients (eg, those treated w/ high doses of diuretics). Patients whose renal function may depend in part on the activity of RAS (eg, patients w/ renal artery stenosis, CKD, severe CHF, or vol depletion) may be at particular risk of developing acute renal failure; periodically monitor renal function. Consider w/holding or discontinuing therapy in patients who develop clinically significant decrease in renal function. Periodically monitor serum K & treat hyperkalemia appropriately. Concomitant use w/ other drugs that may increase serum K. Discontinue use as soon as pregnancy is detected. Decision should be made whether to discontinue nursing or drug, taking into account the importance of the drug to the mother.
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Use In Pregnancy & Lactation
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Adverse Reactions
Dizziness; hyperkalemia.
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Drug Interactions
May result in hyperkalemia w/ other drugs that raise serum K levels. Increased serum conc & toxicity of lithium. May result in deterioration of renal function, including possible acute renal failure, w/ NSAIDs including selective COX-2 inhibitors, in patients who are elderly, vol-depleted (including those on diuretic therapy), or w/ compromised renal function. Antihypertensive effect may be attenuated by NSAIDs. Dual blockade of the RAS w/ ACE inhibitors or aliskiren is associated w/ increased risks of hypotension, syncope, hyperkalemia, & changes in renal function (including acute renal failure). Avoid use w/ aliskiren in patients w/ renal impairment (GFR <60 mL/min).
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Storage
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Description
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Action
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MIMS Class
Angiotensin II Antagonists
ATC Classification
C09CA01 - losartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Regulatory Classification
Rx
Presentation/Packing
Form
Cozalyn 100 FC tab 100 mg
Packing/Price
100's