Clindagen Indications/Uses

Clindamycin is a lincosamide bacteriostatic antibacterial which is used to treat anaerobic infections and some staphylococcal and streptococcal infections. However, because clindamycin may pose a risk of serious adverse effect, this drug is recommended only when penicillin or any alternative drug is not readily available or is inappropriate.
Clindamycin is used to treat gastrointestinal infections caused by Bacteroides fragilis and is an alternative drug for the treatment of infections caused by oropharyngeal strains of B. fragilis.
Clindamycin is also used in the treatment of respiratory tract infections and pharyngitis or tonsillitis caused by Streptococcus pyogenes, as well as in the treatment of other infections caused by Fusobacterium, anaerobic streptococci. Clostridium perfringens and penicillin-resistant strains of Staphylococcus aureus.
Other conditions where clindamycin is of benefit include liver abscess, actinomycosis, biliary tract infections, staphylococcal bone and joint infections. the carrier state of diphtheria, gas gangrene, gynecological infections such as bacterial vaginosis, necrotizing fasciitis, secondary peritonitis, aspiration pneumonia, pneumonia including lung abscess, septicemia, skin disorders with heavy streptococci or anaerobe colonization.
Clindamycin is used in combination with an aminoglycoside or metronidazole to treat penetrating wounds of the abdomen and gut, infections originating in the female genital tract, endometriosis and pelvic inflammatory disease.
Clindamycin is used for endocarditis prophylaxis in patients allergic to penicillin. It is also used as a prophylaxis for surgical infection, in combination with other drugs, and prophylaxis to prevent perinatal streptococcal infections.
Clindamycin exerts some protozoal activity especially in babesiosis, malaria and toxoplasmosis. It is also used with primaquine in the management of pneumocystis pneumonia.