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There is a risk of encephalopathy in cases of administration of beta-lactam antibiotics, including Cefixime, particularly in case of overdose or renal impairment.
Adverse reactions seen at dose levels up to 2 g Cefixime in normal subjects did not differ from the profile seen in patients treated at the recommended doses. Cefixime is not removed from the circulation in significant quantities by dialysis.
No specific antidote exists. General supportive measures are recommended.
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