Usual Adult Dose: 250 mg every 6 hours (Maximum Dose: 4 g/day).
For streptococcal pharyngitis, skin and skin structure infections and uncomplicated cystitis (in patients > 15 years old): 500 mg every 12 hours.
Larger doses (up to 4 g daily) may be needed for more severe infections or those caused by less susceptible organisms. If daily doses of cefalexin greater than 4 g are required, initial therapy with parenteral cephalosporins, in appropriate doses, should be considered.
Elderly: Follow the usual adult dose. However, dosage should be reduced in case of renal impairment.
Patients with Renal Impairment: The initial dose is the same as in patients with normal renal function.
Subsequent doses are based on the patient's creatinine clearance as shown below: See Table 2.

Adult patients receiving intermittent dialysis should be given an additional 500 mg of cefalexin after each dialysis, i.e. a total dosage of up to 1 g on that day.
Usual Duration of Treatment: For mild to moderate infections: 5 to 7 days; For cystitis: 7 to 14 days; For β-hemolytic streptococcal infections: At least 10 days .
Or, as prescribed by a physician.