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Hypertension: Initial dose is 12.5 mg once daily, which should be increased to 25 mg once daily after 2 days. If necessary, it may be further increased to maximum 50 mg in single or divided doses at intervals of at least 2 weeks.
Angina: Initial dose is 12.5 mg twice daily which should be increased after 2 days to 25 mg twice daily.
Heart failure: Initial dose is 3.125 mg with food twice daily which should be increased after 2 weeks to 6.25 mg twice daily, then to maximum 25 mg twice daily in patients less than 85 kg body weight and maximum 50 mg twice daily in patients over 85 kg.
Left Ventricular Dysfunction after myocardial infarction: The initial dose is 6.25 mg twice daily, increased after 3 to 10 days, if tolerated, to 12.5 mg twice daily and then to a target dose of 25 mg twice daily. A lower initial dose may be used in symptomatic patients.
Or as prescribed by a physician.
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