Candez Plus Adverse Reactions

Candesartan: The following undesirable effects have been reported: Body as a Whole: Asthenia, back pain, chest pain, fatigue, fever, malaise, peripheral edema.
Cardiovascular: Hypotension, tachycardia, palpitation, angina pectoris, myocardial infarction.
Gastrointestinal: Nausea, abdominal pain, diarrhea, dyspepsia, vomiting, anorexia, gastroenteritis, stomach discomfort, epigastric pain, stomatitis.
Hematologic: Epistaxis, neutropenia, leukopenia, agranulocytosis, leukocytosis, eosinophilia, anemia.
Liver/Biliary: Abnormal hepatic function, hepatitis, jaundice.
Metabolic and Nutritional/Laboratory Values: Hyperkalemia, hyponatremia, hypertriglyceridemia, hypokalemia, proteinuria; Elevations of the following: total cholesterol, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactic dehydrogenase (LDH), gamma-glutamyl transpeptidase (γ-GTP), blood urea nitrogen (BUN), creatinine phosphokinase (CPK), liver enzymes and/or bilurubin; Reductions of the following: serum total protein, hemoglobin and hematocrit.
Musculoskeletal: Arthralgia, myalgia, rhabdomyolysis (rare).
Nervous System: Dizziness, headache, vertigo, paresthesia, depression, anxiety, somnolence, syncope, lightheadedness, sleepiness.
Respiratory: Upper respiratory tract infections, bronchitis, coughing, dyspnea, pharyngitis, rhinitis, sinusitis.
Skin: Eczema, increased sweating, pruritus, rash, angioedema, urticaria.
Urinary: Renal impairment, renal failure, albuminuria, hematuria, pollakiuria.
Hydrochlorothiazide: The following undesirable effects have been reported: Body as a Whole: Weakness.
Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics, antihypertensive drugs).
Gastrointestinal: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), sialadenitis, cramping, constipation, gastric irritation, anorexia.
Hematologic: Aplastic anemia, agranulocytosis, leucopenia, hemolytic anemia, thrombocytopenia.
Hypersensitivity reactions: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, purpura, urticaria.
Metabolic and Nutritional: Electrolyte imbalance, glycosuria.
Musculoskeletal: Muscle spasm.
Nervous System: Restlessness.
Urinary: Renal impairment, renal failure, interstitial nephritis.
Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidernal necrolysis, alopecia.
Urogenital: Impotence.
Others: Transient blurred vision, xanthopsia.
Candesartan-HCTZ: The following undesirable effects have been reported: Body as a Whole: Inflicted injury, pain, influenza-like symptoms.
Cardiovascular: Extrasystoles, bradycardia, ECG abnormal.
Gastrointestinal: Gastritis.
Metabolic and Nutritional: Hyperuricemia, hyperglycemia, hypokalemia.
Musculoskeletal: Arthrosis, arthritis, leg cramps, sciatica.
Nervous System: Hypesthesia, insomnia.
Skin: Dermatitis.
Urinary: Urinary tract infection, cystitis.
Others: Infection, viral infection, conjunctivitis, tinnitus.