Cetirizine hydrochloride (Benadryl One) is contraindicated to those who are allergic to cetirizine, hydroxyzine, or any component of the formulation.
Cetirizine hydrochloride (Benadryl One) is not recommended to be given to hypokalemic patients with chronic renal failure undergoing hemodialysis. (See Overdosage.)
It should not be given to children with hepatic and renal impairment, who are younger than 6 years of age.
                                
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