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Adults and children 12 years and over: Antitussive: The total daily recommended dose of diphenhydramine is up to 168 mg taken in divided doses of up to 28 mg every 4 hours.
Antihistaminic/Antiemetic: The total daily recommended dose of diphenhydramine is 300 mg taken in divided doses no greater than 25 to 50 mg every 4 to 6 hours.
Nighttime Sleep Aid: Oral dosage is 50 mg at bedtime.
Children aged 6 to less than 12 years: Antitussive: The total daily recommended dose of diphenhydramine is up to 84 mg taken in divided doses of up to 14 mg every 4 hours.
Antihistaminic/Antiemetic: The total daily recommended dose of diphenhydramine is 150 mg taken in divided doses no greater than 12.5 to 25 mg every 4 to 6 hours.
Children aged 4 to less than 6 years: Antitussive: The total daily recommended dose of diphenhydramine is 42 mg taken in divided doses of up to 7 mg every 4 hours.
Diphenhydramine, when indicated as an antitussive, is not recommended for use in children under 4 years of age.
Children aged 2 to less than 6 years: Antihistaminic: The total daily recommended dose of diphenhydramine is 37.5 mg taken in divided doses no greater than 6.25 mg every 4 to 6 hours.
Children under 2 years: Antihistaminic: Do not use in children less than 2 years of age unless directed by a physician.
What should the patient do if they miss a dose: Continue medication based on dosage and/or consult the doctor.
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