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Symptoms of Intoxication: Limited data are available with regard to overdose in humans. The most likely manifestation of overdose would be hypotension and tachycardia. Bradycardia could occur from parasympathetic (vagal) stimulation.
Treatment of Intoxication: If symptomatic hypotension should occur, supportive treatment should be instituted.
Measures depend on the time of medicinal product intake and the kind and severity of symptoms. Stabilization of the cardiovascular system should be given priority. After oral intake, the administration of a sufficient dose of activated charcoal is indicated. Afterward, close monitoring of the vital parameters should be performed. Vital parameters should be corrected if necessary.
Neither Losartan nor the active metabolite can be removed by hemodialysis.
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