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Losartan is given orally as the potassium salt. The maximum hypotensive effect is achieved in about 3 to 6 weeks after starting the treatment.
In hypertension, the usual dose of Losartan Potassium is 50 mg once daily, if necessary, increased to 100 mg daily as a single dose or in two divided doses.
An initial dose of 25 mg once daily should be given to patients with intravascular fluid depletion.
Children weighing 20-50 kg is 25 mg once daily. Children aged 6 years and over may be given an initial dose of 700 mcg/kg once daily with a maximum of 50 mg adjusted according to response.
In diabetic nephropathy, Losartan Potassium is given in an initial dose of 50 mg daily, increased to 100 mg once daily depending on the blood pressure. Or as prescribed by the physician.
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