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There are no adequate and well-controlled studies of ammonium chloride and diphenhydramine (with or without menthol, sodium citrate) in pregnant or breast-feeding women.
Ammonium chloride: It is not known whether ammonium chloride or its metabolites are excreted in breast milk.
Diphenhydramine: There are no adequate and well-controlled clinical studies of diphenhydramine in pregnant or breast-feeding women. Diphenhydramine crosses the placenta and is excreted into breast milk, but levels have not been reported.
The combination of Ammonium chloride/Diphenhydramine (with or without Menthol, Sodium Citrate) should not be used during pregnancy or breastfeeding unless the potential benefit of treatment to the mother outweighs the possible risk to the developing fetus or the nursing infant. Ask a physician before use if the patient is pregnant or breastfeeding.
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