Avator Drug Interactions

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Full Prescribing Info

Drug Interactions

The most serious consequence of drug interactions with Atorvastatin and other statins is the development of myopathy and rhabdomyolysis. Drugs that can cause myopathy when given alone increase the risk of myopathy with all statins: These drugs include fibric acid derivatives (fibrates or gemfibrozil), and nicotinic acid. Atorvastatin is metabolized by cytochrome P450 isoenzyme CYP3A4, as are simvastatin and lovastatin, and interactions may occur with drugs that inhibit this enzyme, including ciclosporin, itraconazole, ketoconazole, erythromycin, clarithromycin, HIV-protease inhibitors, nefazodone, amiodarone, and verapamil; there may also be similar interaction with grapefruit juice.

atorvastatin

Manufacturer:

Lloyd

Distributor:

Corbridge