Avator Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Atorvastatin Ca

Indications/Uses

Reduction of LDL-C, Apo B, & triglycerides, & increase HDL-C in the treatment of hyperlipidaemias, including hypercholesterolaemias & combined (mixed) hyperlipidaemias (type IIa or IIb hyperlipoproteinaemias), hyperlipidaemias (type IIa or IIb hyperlipoproteinaemias), hypertriglyceridaemia (type IV), & dysbetalipoproteinaemia (type III). Adjunctive therapy in patients w/ HoFH who have some LDL-receptor function.

Click to view Avator detailed prescribing information

Dosage/Direction for Use

Initially 10 mg daily, may be adjusted at intervals of 4 wk up to max of 80 mg daily.

Click to view Avator detailed prescribing information

Overdosage

View Avator overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Avoid excessive consumption (>1 L/day) of grapefruit juice.

Contraindications

Active liver disease. Pregnancy & lactation.

Click to view Avator detailed prescribing information

Special Precautions

Discontinue if markedly increased creatinine phosphokinase levels occur or myopathy is diagnosed. Temporarily withhold or discontinue in patients w/ acute serious condition suggestive of myopathy or w/ risk factor predisposing to the development of renal failure secondary to rhabdomyolysis. Increased risk of recurrent hemorrhagic stroke. Increased HbA1c & fasting serum glucose levels. Monitor for increased transaminase levels until abnormalities resolve (signs & symptoms of muscle pain, tenderness or weakness). Use adequate contraceptive measures in women of childbearing potential. Women taking atorvastatin should not breastfeed.

Click to view Avator detailed prescribing information

Use In Pregnancy & Lactation

Click to view Avator detailed prescribing information

Adverse Reactions

GI disturbances. Dizziness, insomnia, headache, blurred vision, dysgeusia & skin rashes.

Click to view Avator detailed prescribing information

Drug Interactions

Increased risk of myopathy w/ fibric acid derivatives (fibrates or gemfibrozil), & nicotinic acid. Interactions may occur w/ drugs that inhibit CYP450 isoenzyme CYP3A4, including ciclosporin, itraconazole, ketoconazole, erythromycin, clarithromycin, HIV-PIs, nefazodone, amiodarone, & verapamil; grapefruit juice.

Click to view Avator detailed prescribing information

Storage

View Avator storage conditions for details to ensure optimal shelf-life.

Description

View Avator description for details of the chemical structure and excipients (inactive components).

Action

View Avator mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Dyslipidaemic Agents

ATC Classification

C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.

Regulatory Classification

Presentation/Packing

Form

Avator FC tab 10 mg

Packing/Price

50's (P9.8/film-coated tab)

Form

Avator FC tab 20 mg

Packing/Price

50's (P16.25/film-coated tab)

Form

Avator FC tab 40 mg

Packing/Price

48's (P22.5/film-coated tab)

Avator

atorvastatin

Manufacturer:

Lloyd

Distributor:

Corbridge