No clinically important drug interactions have been identified and finasteride does not appear to significantly affect the cytochrome P450-linked drug-metabolizing enzyme system. Concomitant drugs that have been studied include propranolol, digoxin, glibenclamide, warfarin, theophylline, and antipyrine.
Finasteride has also been used concomitantly with analgesics including paracetamol, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, anticonvulsants, benzodiazepines, beta-blockers, calcium-channel blockers, cardiac nitrates, diuretics, H2-antagonists, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), and quinolone anti-infectives without evidence of clinically significant adverse interactions.
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