Signs and Symptoms: Experience in adults exposed to doses of up to 900 mg/day for 8 weeks revealed no toxicity. No specific information is available on the treatment of overdosage with Aprovel. 
Management: The patient should be closely monitored, and the treatment should be symptomatic and supportive. Suggested measures include induction of emesis and/or gastric lavage. Irbesartan is not removed from the body by hemodialysis.
                                
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