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Aplosyn Otic (Fluocinolone acetonide) preparations are virtually non-sensitizing and non-irritating. Should sensitivity or idiosyncratic reactions occur, the agent should be discontinued and appropriate steps be taken. Because of the possibility of ototoxicity due to neomycin, otic preparations containing that antibiotic should be used with care in the individuals with a perforated eardrum or long standing chronic otitis media.
If local infections should continue or become severe, appropriate systemic antibacterial therapy, based on susceptibility testing should be considered.
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