Losartan Potassium (Anin 50) should be used with caution in patients with known hypersensitivity to the drugs that act through renin-angiotensin system. Special precaution should be taken when it is administered to the patients with renal and hepatic impairment. Losartan Potassium (Anin 50) should not be used with Potassium-sparing diuretics.