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The attending physician should be informed of the following conditions: Pregnancy, Trimetazidine dihydrochloride should be avoided particularly during the first trimester of pregnancy except when absolutely required. However, there is insufficient evidence to recommend the use of trimetazidine in pregnancy. Animal studies do not reveal any teratogenic effect.
Nursing Mothers, there is no information on the secretion of trimetazidine into breast milk. However, breastfeeding should be discontinued if the use of trimetazidine is considered essential.
Pediatric use, there is no experience with trimetazidine in children.
Impaired Renal and Hepatic Function, no dosage adjustments are required in patients with impaired renal and hepatic function.
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