No drug interactions have so far been reported. In particular, no interactions of trimetazidine with beta-blockers, calcium antagonists, nitrates, heparin, hypolipidemic agents or digitalis have been reported. No further studies have been made regarding the concomitant use of Trimetazidine dihydrochloride (Angimax/Angimax MR) with MAOIs, it is advised that Trimetazidine dihydrochloride (Angimax/Angimax MR) must not be used or coadministered with MAOIs.