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156.25 mg/5 mL & 312.5 mg/5 mL powder for oral suspension: Hypersensitivity to the active substances, to any of the penicillins or to any of the excipients.
History of a severe immediate hypersensitivity reaction (e.g. anaphylaxis) to another beta-lactam agent (e.g. a cephalosporin, carbapenem or monobactam).
History of jaundice/hepatic impairment due to amoxicillin/clavulanic acid (see Adverse Reactions).
228.5 mg/5 mL & 457 mg/5 mL powder for suspension and 642.9 mg/5 mL powder for oral suspension: Hypersensitivity to penicillin or any component of the product.
History of severe immediate hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to another β-lactam antibiotic (e.g. a cephalosporin, carbapenem or monobactam).
Patients with a previous history of cholestatic jaundice/hepatic impairnent associated with Co-amoxiclav or penicillin.
Patients with glandular fever or lymphatic lymphoma should not be given Co-amoxiclav as the amoxicillin component is likely to cause a maculopapular rash.
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