Alfaren Description

Each film-coated tablet contains: Calcium-4-methyl-2-oxo-valerate (α-ketoanalogue to leucine, calcium salt) 101 mg, Calcium-3-methyl-2-oxo-butyrate (α-ketoanalogue to valine, calcium salt) 86 mg, Calcium-2-oxo-3-phenylpropionate (α-ketoanalogue to phenylalanine, calcium salt) 68 mg, Calcium-3-methyl-2-oxo-valerate (α-ketoanalogue to isoleucine, calcium salt) 67 mg, Calcium-DL-2-hydroxy-4-(methylthio)butyrate (α-hydroxyanalogue to methionine, calcium salt) 59 mg, L-Lysine Acetate 105 mg, L-Threonine 53 mg, L-Histidine 38 mg, L-Tyrosine 30 mg, L-Tryptophan 23 mg.
Total nitrogen content per tablet: 36 mg. Calcium content per tablet: 1.25 mmol ≈ 50 mg.
Ketoanalogues + Essential Amino Acids (Alfaren) is a combined preparation for the full supply of indispensable amino acids, with minimum nitrogen. It contains all amino acids essential for uremic patients, five of them are keto or hydroxyanalogues in the form of calcium salts, thus allowing reduction in the nitrogen supply and providing calcium. It is a medication for the treatment of chronic kidney disease patients on conservative management therapy (CKD stage I, II, III). In combination with very low protein diet, it helps in delaying the progression of kidney disease in the predialysis period.