Aldren 70 Dosage/Direction for Use

Alendronic acid (Aldren 70) Tablets must be taken at least one-half hour before the first food, beverage, or medication of the day with plain water only. Other beverages (including mineral water), food, and some medications are likely to reduce the absorption of alendronate sodium. Waiting less than 30 minutes, or taking alendronate sodium tablets with food, beverages (other than plain water) or other medication will lessen the effect of alendronate sodium by decreasing its absorption into the body. To facilitate delivery to the stomach and thus reduce the potential for esophageal irritation, alendronate sodium tablets should only be swallowed upon arising for the day with a full glass of water (6-8 oz) and patients should not lie down for at least 30 minutes and until after their first food of the day. Alendronate sodium Tablets should not be taken at bedtime or before arising for the day. Failure to follow these instructions may increase the risk of esophageal adverse experiences. Patients should receive supplemental calcium and vitamin D, if dietary intake is inadequate. No dosage adjustment is necessary for the elderly or for patients with mild-to-moderate renal insufficiency (creatinine clearance 35 to 60 mL/min). Alendronate sodium Tablets are not recommended for patients with more severe renal insufficiency (creatinine clearance <35 mL/min) due to lack of experience.
Treatment of osteoporosis in postmenopausal women: The recommended dosage is: one 70 mg tablet once weekly or, one 10 mg tablet once daily.
Treatment to increase bone mass in men with osteoporosis: The recommended dosage is one 10 mg tablet once daily.
Prevention of osteoporosis in postmenopausal women: The recommended dosage is: one 35 mg tablet once weekly or, one 5 mg tablet once daily.
Treatment of glucocorticoid-induced osteoporosis in men and women: The recommended dosage is one 5 mg tablet once daily, except for postmenopausal women not receiving estrogen, for whom the recommended dosage is one 10 mg tablet once daily.
Paget's disease of bone in men and women: The recommended treatment regimen is 40 mg once a day for six months.