Central nervous system: Drowsiness, headache, insomnia have been observed rarely during therapy (less than 1%).
Gastrointestinal: Nausea, vomiting, diarrhoea, dyspepsia or epigastric pain, constipation, heartburn and anorexia have been described rarely during oral therapy with glucosamine.
Skin: Skin reactions such as erythema and pruritus have been reported with therapeutic administration of glucosamine.
Evaluation of the undesirable effects is based on the following frequency information: Very common: ≥1/10; Common: ≥1/100 to <1/10; Uncommon: ≥1/1,000 to <1/100; Rare: ≥1/10,000 to <1,100; Very Rare: <1/10,000; Not known: cannot be estimated from the available data. (See table.)

Cases of hypercholesterolemia have been reported, but a causal link has not been demonstrated.
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