Twinrix Caution For Usage

Incompatibilities: Twinrix should not be mixed with other vaccines in the same syringe.
Use and Handling: The vaccine should be re-suspended before use. When re-suspended, the vaccine will have a uniform hazy white appearance.
Upon storage, a fine white deposit with a clear colourless layer above may be observed.
Re-suspension of the vaccine to obtain a uniform hazy white suspension.
The vaccine can be re-suspended following the steps as follows: 1. Hold the syringe upright in a closed hand.
2. Shake the syringe by tipping it upside down and back again.
3. Repeat this action vigorously for at least 15 seconds.
4. Inspect the vaccine again: a. If the vaccine appears as a uniform hazy white suspension, it is ready to use - the appearance should not be clear.
b. If the vaccine still does not appear as a uniform hazy white suspension - tip upside down and back again for at least another 15 seconds - then inspect again.
The vaccine should be inspected visually for any foreign particulate matter and/or abnormal physical appearance prior to administration. In the event of either being observed, do not administer the vaccine.
Instructions for the pre-filled syringe: Hold the syringe by the barrel, not by the plunger.
Unscrew the syringe cap by twisting it anticlockwise.
To attach the needle, connect the hub to the Luer Lock Adaptor and rotate a quarter turn clockwise until it felt locked.
Do not pull the syringe plunger out of the barrel. If it happens, do not administer the vaccine.
Disposal: Any unused product or waste material should be disposed of in accordance with local requirements.