The most frequent adverse reactions of metoclopramide are restlessness, drowsiness, fatigue and lassitude that occur in approximately 10% of patients. Less frequently, insomia, headache, dizziness, nausea, bowel disturbance or extrapyramidal symptoms may occur. Rarely depression and persistent dyskinesia have been reported.
A single instance of supraventricular tachycardia following intramuscular administration has been reported.