SW Metoclopramide Dosage/Direction for Use

Adults: The recommended single dose is 10 mg, repeated up to three times daily.
The maximum recommended daily dose is 30 mg or 0.5 mg/kg body weight.
The maximum recommended treatment duration is 5 days.
Prevention of delayed chemotherapy induced nausea and vomiting (CINV) (paediatric patients aged 1-18 years): The recommended dose is 0.1 to 0.15 mg/kg body weight, repeated up to three times daily by oral route. The maximum dose in 24 hours is 0.5 mg/kg body weight.
Dosing table: (See table.)

Click on icon to see table/diagram/image

The maximum treatment duration is 5 days for prevention of delayed chemotherapy induced nausea and vomiting (CINV).
Tablet is not suitable for use in children weighing less than 30 kg. Other pharmaceutical forms may be more appropriate for administration to this population.
Frequency of administration: A minimum interval of 6 hours between two administrations is to be respected, even if vomiting or rejection of the dose occurs.
Special population: Elderly: In elderly patients, a dose reduction should be considered, based on renal and hepatic function and overall frailty.
Renal impairment: In patients with end stage renal disease (Creatinine clearance ≤15 ml/min), the daily dose should be reduced by 75%.
In patients with moderate to severe renal impairment (Creatinine clearance 15-60 ml/min), the dose should be reduced by 50%.
Hepatic impairment: In patients with severe hepatic impairment, the dose should be reduced by 50%.