Glucosamine treats the underlying cause of osteoarthritis and the therapeutic effect can only be seen after 2 to 3 weeks. Therefore, it is advisable to take an analgesic or anti-inflammatory drug if required during the first 2 to 3 weeks of therapy with glucosamine. Glucosamine (and chondroitin/MSM) are not meant to replace NSAIDs in cases of intense pain as this is a causal therapy.
Glucosamine may increase insulin resistance. Glucosamine increases insulin resistance in normal and experimentally diabetic animals. In these animals, intravenous glucosamine significantly decreases the rate of glucose uptake in skeletal muscle.
Those with type 2 diabetes and those who are overweight and have problems with glucose tolerance should have their blood sugar levels carefully monitored if they use glucosamine supplements.
Administration during the first three months of pregnancy must be avoided.
Safety and effectiveness have not been established in children, therefore children should avoid using glucosamine.
The administration in patients with severe hepatic or renal insufficiency should be made under medical supervision.
A doctor should be consulted in order to exclude the presence of other joint conditions/diseases for which an alternative treatment should be considered.
This product contains glucosamine derived from seafood, therefore should not be given to patients who are allergic to seafood.
This product contains chondroitin from bovine source.
Effects on Ability to Drive and Use Machine: No effects on the ability to drive or to operate machines are expected.
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