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The initial dose is 1 tablet (3 mg) of dinoprostone inserted high into the posterior fornix. A second tablet may be inserted after 6-8 hours if labor has not been established. The maximum or total dose in 24 hours is 6 mg.
Usage is restricted to qualified healthcare professionals and to hospitals and clinics with specialised obstetric units with facilities for continuous monitoring.
The recommended dose should not be exceeded, and the dosing interval should not be shortened as this increases the risk of uterine hyperstimulation, uterine rupture, uterine haemorrhage, foetal and neonatal death.
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