Pico-Salax Use In Pregnancy & Lactation

Pregnancy: There are no data with PICO-SALAX use in pregnant women to determine a drug-associated risk of adverse developmental outcomes.
In animal reproduction studies, no adverse developmental effects were observed in pregnant rats when sodium picosulfate, magnesium oxide, and anhydrous citric acid were administered orally at doses 1.2 times the recommended human dose based on body surface area during organogenesis.
PICO-SALAX should not be used during pregnancy unless the clinical condition of the woman requires treatment.
Breastfeeding: There is insufficient data on the use of PICO-SALAX in nursing mothers, the effects on the breastfed infant, or the effects on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for PICO-SALAX and any potential adverse effects on the breastfed infant from PICO-SALAX.
Fertility: Studies with PICO-SALAX in animals have shown no impairment of fertility or embryo-fetal toxicity. In studies with sodium picosulfate alone, embryofetal toxicity has been observed in rats and rabbits at very high doses.