Nimedine Caution For Usage

Incompatibilities: This medicinal product must not be mixed with other medicinal products except those mentioned in Instructions for Use as follows.
Instructions for Use: Each vial is for single use only.
Reconstitution: Contents of each vial must be transferred to 100 ml of an appropriate infusion solution: 0.9% sodium chloride. In exceptional circumstances where 0.9% sodium chloride cannot be used for clinical reasons 5% glucose may be used instead.
A suggested procedure is to add approximately 10 ml of the appropriate infusion solution to the vial. Shake well and transfer the resulting mixture to the infusion solution container.
CAUTION: THE MIXTURE IS NOT FOR DIRECT INFUSION.
Repeat with an additional 10 ml of infusion solution to ensure complete transfer of vial contents to the infusion solution. The resulting mixture should be agitated until clear.
The concentration of the reconstituted solution following the previously mentioned procedure is approximately 5 mg/ml for both imipenem and cilastatin.
Variations of colour, from colourless to yellow, do not affect the potency of the product.
Any unused product or waste material should be disposed of in accordance with local requirements.