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Loperamide HCl is contraindicated in patients with a known hypersensitivity to Loperamide HCl or to any of the excipients.
Loperamide HCl should not be used in children under 6 years of age.
Loperamide HCl should not be used as the primary therapy: in patients with acute dysentery, which is characterized by blood in stools and high fever; in patients with acute ulcerative colitis; in patients with bacterial enterocolitis caused by invasive organisms including Salmonella, Shigella, and Campylobacter; in patients with pseudomembranous colitis associated with the use of broad-spectrum antibiotics.
Loperamide HCl should not be used when inhibition of peristalsis is to be avoided due to the possible risk of significant sequelae including ileus, megacolon and toxic megacolon. Loperamide HCl must be discontinued promptly when constipation, abdominal distension or ileus develop.
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