The dose of Foliculin to produce maturation of follicle must be individualized for each patient.
It is recommended that initial dose to any patient should be 75 I.U. of Foliculin per day administered subcutaneous for at least 7 days followed by HCG 5000 I.U. to 10000 I.U. one day after last dose of Foliculin.
Courses of treatment should be no longer than 12 days.
If there is evidence of ovulation but no pregnancy, repeat previously mentioned dosage regimen for at least 2 or more courses before increasing the dose to Foliculin 150 IU per day for 7-12 days. As stated previously this dose should be followed by HCG 5000 I.U. to 10000 I.U. one day after last dose of Foliculin. If evidence of ovulation is present but pregnancy is not sure repeat the same dose for 2 more courses, Doses larger than this are not routinely recommended.
In-vitro Fertilization: In-vitro fertilization therapy with Foliculin should be initiated in the early follicular phase (cycle day 2 or 3) at a dose of 150 I.U. per day until sufficient follicular development is attained. In most cases therapy should not exceed beyond 10 days.
Reconstitution Instructions: Reconstitute the contents of vial containing Foliculin in 1ml of Sodium Chloride Injection BP and administer subcutaneous immediately.
Route of Administration: Intramuscular (IM) + Subcutaneous (SC).
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