Eurobio Bio-SMEDDS Q10 200 mg

Oblong, opaque red soft capsule with orange suspension.
Each soft vegetable capsule contains: Ubidecarenone (Coenzyme Q10) 200 mg.

Pharmacology: Pharmacodynamics: Mechanism of Action: Coenzyme Q10 is a naturally occurring coenzyme involved in electron transport in the mitochondria. Adequate amounts of Coenzyme Q10 are necessary for cellular respiration and ATP production. Due to its involvement in ATP synthesis, Coenzyme Q10 affects the function of all cells in the body, making it essential for the health of all tissues and organs.
Coenzyme Q10 also functions as an intercellular antioxidant at the mitochondrial level, accounting for its benefit in neurodegenerative diseases, male infertility, and periodontal disease. It is biosynthesized in the body and shares a synthesis pathway with cholesterol. Coenzyme Q10 levels decrease with aging in humans.
Pharmacokinetics: Coenzyme Q10 is absorbed from the small intestine, incorporated into chylomicrons for lymphatic transport, and finally to the blood and tissues. Absorption of Coenzyme Q10 after oral administration is poor. Its absorption is highly variable and depends not only on food intake but also on the amount of lipids present in the food.
Absorption is lower on an empty stomach and greater when taken with food of high lipid content. In the blood Coenzyme Q10 is predominantly associated with lipoproteins, including VLDL, LDL and HDL. The main elimination of Coenzyme Q10 occurs via the biliary system and into the feces.

Coenzyme Q10 (Ubidecarenone) may be indicated in cardiovascular disease, particularly in congestive heart failure. It may also be indicated to correct reduced blood levels of Coenzyme Q10 that results from the use of HMG-CoA reductase inhibitors used to treat elevated cholesterol levels. It appears to have usefulness in the management of periodontal disease. Used as a health supplement.

1 soft vegetable capsule once daily with food or as directed by doctor or pharmacist.

Taken at recommended dosage, no known special precautions.

Coenzyme Q10 is widely considered safe and well-tolerated across a broad dosage range. Most side effects are mild and transient. Occasional reports of nausea, anorexia, or skin eruptions have been reported with Coenzyme Q10 supplementation.

Cholesterol-lowering drugs such as statins inhibit the enzyme HMG-CoA reductase, required for synthesis of cholesterol as well as Coenzyme Q10, resulting in decreased serum CoQ10. Beta blockers such as propranolol and metoprolol, phenothiazines and tricyclic antidepressants have been shown to inhibit Coenzyme Q10-dependant enzymes.

Store in a dry place below 30°C. Protect from light and moisture.
Shelf Life: 2 years.

Supplements & Adjuvant Therapy

C01EB09 - ubidecarenone ; Belongs to the class of other cardiac preparations.

NP