Eurobio Bio-SMEDDS Q10 200 mg Mechanism of Action

Pharmacology: Pharmacodynamics: Mechanism of Action: Coenzyme Q10 is a naturally occurring coenzyme involved in electron transport in the mitochondria. Adequate amounts of Coenzyme Q10 are necessary for cellular respiration and ATP production. Due to its involvement in ATP synthesis, Coenzyme Q10 affects the function of all cells in the body, making it essential for the health of all tissues and organs.
Coenzyme Q10 also functions as an intercellular antioxidant at the mitochondrial level, accounting for its benefit in neurodegenerative diseases, male infertility, and periodontal disease. It is biosynthesized in the body and shares a synthesis pathway with cholesterol. Coenzyme Q10 levels decrease with aging in humans.
Pharmacokinetics: Coenzyme Q10 is absorbed from the small intestine, incorporated into chylomicrons for lymphatic transport, and finally to the blood and tissues. Absorption of Coenzyme Q10 after oral administration is poor. Its absorption is highly variable and depends not only on food intake but also on the amount of lipids present in the food.
Absorption is lower on an empty stomach and greater when taken with food of high lipid content. In the blood Coenzyme Q10 is predominantly associated with lipoproteins, including VLDL, LDL and HDL. The main elimination of Coenzyme Q10 occurs via the biliary system and into the feces.