Starxon Special Precautions

Before administration of Starxon, any hypersensitivity to cephalosporins and penicillin should be determined. Starxon is excreted via gallbladder and kidneys, therefore, monitoring of serum level in patients with renal dysfunction should be done. Caution must be exercised in patients with history of gastrointestinal disease, especially colitis. Prothrombin time should be monitored in patients with vitamin K synthesis disorders or lower intake of vitamin K. Prolonged treatment may result in overgrowth of nonsensitive microorganisms. If superinfections occur, administration should be discontinued and appropriate therapy must be implemented. Pseudomembranous colitis has been reported with the use of antibacterial agents, including ceftriaxone, therefore, the diagnosis should be reconsidered if diarrhoea occurs.
Use in pregnancy & lactation: Starxon may be used in pregnant women only if strictly indicated. Use with caution in nursing mothers, as ceftriaxone passes into breast milk.
Use in children: Safety and effectiveness in neonates, infants and children have been determined according to the recommended doses. Administration must be done with caution in neonates with hyperbilirubinemia, especially premature babies.