Ricoxa Dosage/Direction for Use

RICOXA should be given for the shortest possible duration and the lowest effective daily dose should be used.
Osteoarthritis: The recommended dose is 60 mg once daily.
Rheumatoid arthritis: The recommended dose is 60 mg once daily. In some patients with persistent symptoms, the dose may be increased to 90 mg.
Ankylosing spondylitis: The recommended dose is 60 mg once daily. In some patients with persistent symptoms, the dose may be increased to 90 mg.
Chronic Musculoskeletal Pain: The recommended dose is 60 mg once daily.
Acute Gouty Arthritis: The recommended dose is 120 mg once daily. RICOXA should be used only for periods of acute symptoms limited to a maximum of 8 days.
Postoperative Toothache: The recommended dose is 90 mg once daily.
Doses greater than those recommended for each indication have not shown additional efficacy or have not been studied. Therefore, the dose for each indication is the maximum recommended dose.
Elderly, Gender, Race: No dose adjustment of RICOXA is necessary for the elderly or based on gender or race.
Hepatic insufficiency: In patients with mild hepatic insufficiency (Child-Pugh score 5-6), a dose of 60 mg once daily should not be exceeded. In patients with moderate hepatic insufficiency (Child-Pugh score 7-9), the dose should be reduced; a dose of 60 mg daily should not be exceeded. There are no clinical or pharmacokinetic data in patients with severe hepatic insufficiency (Child-Pugh score >9).
Renal insufficiency: In patients with advanced renal disease (creatinine clearance <30 mL/min), treatment with RICOXA is not recommended. No dose adjustment is necessary for patients with lesser degrees of renal insufficiency (creatinine clearance ≥30 mL/min).