Ricoxa Adverse Reactions

The following adverse drug reactions were reported in clinical studies in patients with osteoarthritis, rheumatoid arthritis, or chronic low back pain treated for up to 12 weeks. They occurred in ≥1% of patients treated with Etoricoxib and were greater in incidence than placebo: Asthenia/fatigue, dizziness, lower extremity edema, hypertension, dyspepsia, heartburn, nausea, headache, increased alanine aminotransferase, increased aspartate aminotransferase.
These adverse reactions were similar in patients with osteoarthritis or rheumatoid arthritis treated with Etoricoxib for 1 year or longer.
Other adverse reactions: Blood and lymphatic system disorders: Thrombocytopenia.
Immune system disorders: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions including shock.
Metabolic and nutritional disorders: Hyperkalemia.
Psychiatric disorders: Anxiety, insomnia, confusion, hallucinations, depression, poor rest.
Nervous system disorders: Dysgeusia, somnolence.
Eye disorders: Blurred vision.
Cardiac disorders: Congestive heart failure, palpitations, angina, arrhythmias.
Vascular disorders: Hypertensive crisis.
Respiratory, thoracic and mediastinal disorders: Bronchospasm.
Gastrointestinal disorders: Abdominal pain, mouth ulcers, gastric ulcers including perforation and bleeding (especially in elderly patients), vomiting, diarrhea.
Hepatobiliary disorders: Hepatitis, jaundice, liver failure.
Skin and subcutaneous tissue disorders: Angioedema, pruritus, erythema, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria, fixed drug eruption.
Renal and urinary tract disorders: Renal insufficiency, including renal failure.