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Depletion of potassium serum level may increase probability of digitalis intoxication.
Co-administration of drugs or liquids containing cations may reduce the effectiveness of calcium resin binding to potassium.
Aluminium hydroxide, intestinal obstruction due to co-administration of aluminium hydroxide has been reported when taken in combination with resin.
Digoxin: The toxic effects of digoxin to the heart, especially ventricular arrhythmias and AV nodal depression, can be exaggerated by hypokalemia and/or hypercalcemia.
