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Hematological: Granulocytopenia or eosinophilia, thrombocytopenia.
Hepatic: an increase in SGOT, SGPT or alkaline phosphatase can occur.
Kidney: renal insufficiency may occur.
Digestion: Severe colitis, such as pseudomembranous colitis can occur, which is indicated by the presence of blood in the stool. Abdominal pain or diarrhea rarely occurs vomiting, diarrhea, abdominal pain, abdominal discomfort, heartburn or anorexia, nausea, satiety or constipation.
Respiratory: interstitial pneumonia or PIE syndrome, fever, cough, dyspnea, abnormal chest x-ray or eosinophilia.
Changes in bacterial flora: Stomatitis or candidiasis.
Vitamin deficiency: Vitamin K deficiencies such as hypoprothrombinemia or bleeding tendencies or vitamin B group deficiencies (such as glossitis, stomatitis, anorexia, or neuritis).
Others: Headaches or dizziness.
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