Cetamol Dosage/Direction for Use

Intravenous route: The 50 mL bottle is restricted to children weighing from 10 kg (approximately one year old) to 33 kg. The 100 mL bottle is restricted to adults, adolescents and children weighing more than 33 kg (approximately 11 years old).
Posology: Adolescents and adults weighing more than 50 kg: CETAMOL 1 g per administration, i.e. one 100 mL bottle, up to four times a day. The minimum interval between each administration must be 4 hours. The maximum daily dose must not exceed 4 g.
Children weighing more than 33 kg (approximately 11 years old), adolescents and adults weighing less than 50 kg: CETAMOL 15 mg/kg per administration, i.e. 1.5 mL solution per kg up to four times a day. The minimum interval between each administration must be 4 hours. The maximum daily dose must not exceed 60 mg/kg (without exceeding 3 g).
Children weighing more than 10 kg (approximately1 year old) and weighing less than 33 kg: CETAMOL 15 mg/kg per administration, i.e. 1.5 mL solution per kg up to four times a day. The minimum interval between each administration must be 4 hours. The maximum daily dose must not exceed 60 mg/kg (without exceeding 2 g).
Severe renal insufficiency: It is recommended, when giving CETAMOL to patients with severe renal impairment (creatinine clearance ≤30 mL/min), to increase the minimum interval between each administration to 6 hours.
Method of Administration: CETAMOL solution is administered as a 15-minute intravenous infusion. It can also be diluted in a 0.9% Sodium Chloride solution or a 5% Glucose solution up to one tenth. In this case, use the diluted solution within the hour following its proportion (infusion time included). As for all solutions for infusion presented in glass bottle, it is reminded that a close monitoring is needed notably at the end of the infusion, regardless the administration route. This monitoring at the end of the perfusion applies particularly for central route infusion, in order to avoid embolism.