Yaz Contraindications

YAZ should not be used in women with: A history of or actual thrombophlebitis or thromboembolic disorders.
A history of or actual cerebrovascular disorders.
A history of or actual myocardial infarction or coronary artery disease.
Valvular heart disease with complications.
A history of or actual prodromi of a thrombosis (eg, transient ischemic attack, angina pectoris).
Presence of severe or multiple risk factor(s) for arterial or venous thrombosis: severe hypertension (persistent values of ≥160/100 mmHg); hereditary or acquired predisposition for venous or arterial thrombosis, such as Factor V Leiden mutation and activated protein C (APC) resistance, antithrombin-III-deficiency, protein C deficiency, protein S deficiency, hyperhomocysteinemia and antiphospholipid antibodies (anticardiolipin antibodies, lupus anticoagulant); severe dyslipoproteinemia; smoking, if over age 35; diabetes mellitus with vascular involvement; major surgery associated with an increased risk of postoperative thromboembolism; prolonged immobilization.
Use with the Hepatitis C virus combination drug regimen ombitasvir, paritaprevir, ritonavir, with or without dasabuvir (see Precautions).
Active liver disease or history of, or actual benign or malignant liver tumors.
Known or suspected carcinoma of the breast.
Carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia.
Undiagnosed abnormal vaginal bleeding.
Steroid-dependent jaundice, cholestatic jaundice, history of jaundice in pregnancy.
Any ocular lesion arising from ophthalmic vascular disease, such as partial or complete loss of vision or defect in visual fields.
Known or suspected pregnancy.
Current or history of migraine with focal aura.
History of or actual pancreatitis if associated with severe hypertriglyceridemia.
Renal insufficiency.
Hepatic dysfunction.
Adrenal insufficiency.
Hypersensitivity to this drug or to any ingredient in the formulation or component of the container. For a complete listing, see Description.