Embryo-Fetal Toxicity: Exposure to WELIREG during pregnancy can cause embryo-fetal harm.
Verify pregnancy status prior to the initiation of WELIREG.
Advise patients of these risks and the need for effective non-hormonal contraception. WELIREG can render some hormonal contraceptives ineffective [see Embryo-Fetal Toxicity under Precautions; Effect of WELIREG on Other Drugs under Interactions; Pregnancy and Females and Males of Reproductive Potential under Use in Pregnancy & Lactation].